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The Shiels Laboratory


Brette, F., Shiels, H., Galli, G., Cros, C., Incardona, J., Scholz, N., & Block, B. A. (2017). A Novel Cardiotoxic Mechanism for a Pervasive Global Pollutant. Scientific Reports. DOI: 10.1038/srep41476. Publication link: c0942fc9-26df-4483-a5a9-83c009dcbed1
McKenzie, D. J., Axelsson, M., Chabot, D., Claireaux, G., Cooke, S. J., Corner, R. A., ... Metcalfe, J. D. (2016). Conservation physiology of marine fishes: state of the art and prospects for policy. Conservation Physiology, 4(1). DOI: 10.1093/conphys/cow046. Publication link: ba29bd80-7239-4d6a-a019-de8f69d6aeb7
Ozolina, K., Shiels, H. A., Ollivier, H., & Claireaux, G. (2016). Intraspecific individual variation of temperature tolerance associated with oxygen demand in the European sea bass (Dicentrarchus labrax). Conservation Physiology, 4(1), 1-10. DOI: 10.1093/conphys/cov060. Publication link: 4fd44ae1-759c-4a31-818d-9d03ed6b1841
Smyllie, N. J., Pilorz, V., Boyd, J., Meng, Q-J., Saer, B., Chesham, J. E., ... Loudon, A. (2016). Visualizing and Quantifying Intracellular Behavior and Abundance of the Core Circadian Clock Protein PERIOD2. Current Biology, 26(14), 1880-1886. DOI: 10.1016/j.cub.2016.05.018. Publication link: 68dc4a96-edb1-4b12-8c06-31cfbc1aea17 | PubMed:27374340
Joyce, W., Ozolina, K., Mauduit, F., Ollivier, H., Claireaux, G., & Shiels, H. A. (2016). Individual variation in whole-animal hypoxia tolerance is associated with cardiac hypoxia tolerance in a marine teleost. Royal Society of London. Proceedings B. Biological Sciences, 12(1), [0708]. DOI: 10.1098/rsbl.2015.0708. Publication link: d2cdd553-1f70-4b40-8598-8f2e8322587f
Chowdhury, S. K., Liu, W., Zi, M., Li, Y., Wang, S., Tsui, H., ... Wang, X. (2016). Stress-Activated Kinase MKK7 Governs Epigenetics of Cardiac Repolarization for Arrhythmia Prevention. Circulation. DOI: 10.1161/CIRCULATIONAHA.116.022941. Publication link: 0920f2b0-ff0b-46b8-a36e-fb81936c6f55
Keen, A., Shiels, H., & Crossley , D. A. (2016). Cardiovascular function, compliance and connective tissue remodeling in the turtle, Trachemys scripta, following thermal acclimation. American journal of physiology. Regulatory, integrative and comparative physiology, 311(1), 133-143. DOI: 10.1152/ajpregu.00510.2015. Publication link: 64f1785f-7084-45da-af15-44f908144655
Fenkes, M., Shiels, H. A., Fitzpatrick, J. L. L., & Nudds, R. L. (2016). The potential impacts of migratory difficulty, including warmer waters and altered flow conditions, on the reproductive success of salmonid fishes. Comparative Biochemistry and Physiology. Part A: Molecular & Integrative Physiology, 193, 11-21. DOI: 10.1016/j.cbpa.2015.11.012, 10.1016/j.cbpa.2015.11.012. Publication link: 7e363947-a8dd-48cb-a8da-59e752c597cd
Shiels, H. A., Galli, G. L. J., & Block, B. A. (2015). Cardiac function in an endothermic fish: cellular mechanisms for overcoming acute thermal challenges during diving.Proceedings. Biological sciences / The Royal Society, 282(1800), [20141989]. DOI: 10.1098/rspb.2014.1989. Publication link: 31537d8a-5de2-4b74-9a76-c0f74f9bfd2f | PubMed:25540278
Shiels, H., shiels, H., & Sitsapesan, R. (2015). Is there something fishy about the regulation of the ryanodine receptor in the fish heart?Experimental Physiology, 100(12), 1412-1420. DOI: 10.1113/EP085136. Publication link: 12bde02f-12b6-45e1-8926-e76d06af9199
Keen, A. N., Fenna, A. J., McConnell, J. C., Sherratt, M. J., Gardner, P., & Shiels, H. A. (2015). The Dynamic Nature of Hypertrophic and Fibrotic Remodeling of the Fish Ventricle.Frontiers in physiology, 6, [427]. DOI: 10.3389/fphys.2015.00427. Publication link: 74d08c3d-ca71-4396-9e4c-d74305e6221a | PubMed:26834645
Lea, J. M. D., Keen, A. N., Nudds, R. L., & Shiels, H. A. (2015). Kinematics and energetics of swimming performance during acute warming in brown trout (Salmo trutta). Journal of Fish Biology, [online at]. DOI: doi:10.1111/jfb.12788. Publication link: 8caa8b46-5d18-49cf-9f45-033baf17d7bb
Hassinen, M., Haverinen, J., Hardy, M. E., Shiels, H. A., & Vornanen, M. (2015). Inward rectifier potassium current (I K1) and Kir2 composition of the zebrafish (Danio rerio) heart.Pflugers Archiv : European journal of physiology. DOI: 10.1007/s00424-015-1710-8. Publication link: 9a13b9f7-3f30-45df-a2b4-e03535d0d2ca | PubMed:25991088
Wood, S. H., Christian, H. C., Miedzinska, K., Saer, B., Johnson, M., Paton, B., ... Loudon, A. (2015). Binary switching of calendar cells in the pituitary defines the phase of the circannual cycle in mammals. Current Biology, 25(20), 2651-2662. DOI: 10.1016/j.cub.2015.09.014. Publication link: bed8849c-3169-4b45-bb56-c6976b03d1b3 | PubMed:26412130
Grunow, B., Mohamet, L., & Shiels, H. A. (2015). Generating an In Vitro 3D Cell Culture Model from Zebrafish Larvae for Heart Research.The Journal of experimental biology. DOI: 10.1242/jeb.118224. Publication link: bf77c0c8-7ce6-4918-a64b-466377aa0799 | PubMed:25714567
Cros, C., Salle, L., Warren, D. E., Shiels, H. A., & Brette, F. (2014). The calcium stored in the sarcoplasmic reticulum acts as a safety mechanism in rainbow trout heart.American journal of physiology. Regulatory, integrative and comparative physiology, 307, R1493-R1501. DOI: 10.1152/ajpregu.00127.2014. Publication link: 3570954f-a818-4686-a1e1-8696604d5f21 | PubMed:25377479
Haworth, T. E., Haverinen, J., Shiels, H. A., & Vornanen, M. (2014). Electrical excitability of the heart in a Chondrostei fish, the Siberian sturgeon (Acipenser baerii).American journal of physiology. Regulatory, integrative and comparative physiology, 307(9). DOI: 10.1152/ajpregu.00253.2014. Publication link: 615d1286-073b-495d-9ccf-36ce68618bc4 | PubMed:25163915
Nudds, R. L., John, E. L., Keen, A. N., & Shiels, H. A. (2014). Rainbow trout provide the first experimental evidence for adherence to a distinct Strouhal number during animal oscillatory propulsion.The Journal of experimental biology, 217(Pt 13), 2244-2249. DOI: 10.1242/jeb.102236. Publication link: 6de8a812-cbd3-48cc-a6a0-12710ea22efb | PubMed:25141343
Shiels, H. A., & Galli, G. L. J. (2014). The Sarcoplasmic Reticulum and the Evolution of the Vertebrate Heart.Physiology, 29(6), 456-469. DOI: 10.1152/physiol.00015.2014. Publication link: 85ebf2ab-b4f4-4ccc-a309-e5587e9b627f | PubMed:25362639